Breast cancer

Signs and symptoms

Knowing the signs and symptoms of breast cancer may help save your life. When the disease is discovered early, you have more treatment options and a better chance for a cure.Most breast lumps aren't cancerous. Yet the most common sign of breast cancer for both men and women is a lump or thickening in the breast. Often, the lump is painless. Other potential signs of breast cancer include:

• A spontaneous clear or bloody discharge from your nipple, often associated with a breast lump
• Retraction or indentation of your nipple
• A change in the size or contours of your breast
• Any flattening or indentation of the skin over your breast
• Redness or pitting of the skin over your breast, like the skin of an orange

A number of conditions other than breast cancer can cause your breasts to change in size or feel. Breast tissue changes naturally during pregnancy and your menstrual cycle. Other possible causes of noncancerous (benign) breast changes include fibrocystic changes, cysts, fibroadenomas, infection or injury.

If you find a lump or other change in your breast - even if a recent mammogram was normal - see your doctor for evaluation. If you haven't yet gone through menopause, you may want to wait through one menstrual cycle before seeing your doctor. If the change hasn't gone away after a month, have it evaluated promptly.

What is mesothelioma?

Mesothelioma is a type of cancer. It is a cancer of mesothelial cells. These cells cover the outer surface of most of our internal body organs, forming a lining that is sometimes called the mesothelium. So this is where this type of cancer gets its name.

The pleura
The tissues lining (or covering) the lungs are called the pleura. There are two pleura. These can be called pleural membranes. The gap between them is called the pleural space. The pleura are fibrous sheets. They help to protect the lungs. They produce a lubricating fluid that fills the gap between the two pleura. This helps the lungs to move smoothly in the chest when they are inflating and deflating as we breathe.

Mesothelioma is most often diagnosed in the pleura. This is known as pleural mesothelioma. Because it is so close, pleural mesothelioma can also affect the sheet of tissue covering the heart - the pericardium. Doctors call the pericardium the lining, although it is on the outside of the heart. It protects the heart and allows it to move smoothly within the sac that surrounds it. So it does much the same job for the heart as the pleura do for the lungs. read more

Cancer: The facts

One in three of us will be diagnosed with cancer during our life.

The disease tends to affect older people - but can strike at any time.

Excluding certain skin cancers, there were more than 270,000 new cases of the disease in 2001 - and the rate is increasing by about 1% a year.

Some cancer, such as breast, are becoming more common, while new cases of lung cancer fall away due to the drop in the number of smokers.

However, while the overall number of new cancers is not falling, the good news is that successful treatment rates for many of the most common types are improving rapidly.

BBC News Online has produced, in conjunction with Cancer Research UK, a guide to some of the most common forms of cancer and the treatments used to tackle them. read more

Heart Disease & Stroke

INTRODUCTION

The UK has one of the highest rates of death from heart disease in the world - one British adult dies from the disease every three minutes - and stroke is the country's third biggest killer, claiming 70,000 lives each year.
Heart attacks occur when blood flow is blocked, often by a blood clot, while strokes are caused either by blocked or burst blood vessels in the brain. A range of other conditions, including heart failure, when blood is not pumped properly around the body, and congenital heart defects can also cause long term problems, and even death, for sufferers.

HIV infections

The human immunodeficiency virus (HIV) is a retrovirus that infects cells of the human immune system, destroying or impairing their function. In the early stages of infection, the person has no symptoms. However, as the infection progresses, the immune system becomes weaker, and the person becomes more susceptible to so-called opportunistic infections.

The most advanced stage of HIV infection is acquired immunodeficiency syndrome (AIDS). It can take 10-15 years for an HIV-infected person to develop AIDS; antiretroviral drugs can slow down the process even further.

HIV is transmitted through unprotected sexual intercourse (anal or vaginal), transfusion of contaminated blood, sharing of contaminated needles, and between a mother and her infant during pregnancy, childbirth and breastfeeding. read more